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( B ) Schematic of renal carnitine synthesis pathway where BBOX1 (surrounded with red) is the rate limiting enzyme

( Reference Martinov, Vitvitsky and Mosharov 39 ) , in a mathematical modelling study of SAM metabolism in the liver, stated that when SAM levels are low, priority for this substrate goes to transmethylation reactions, promoting reduction of the trans-sulfuration pathway

We report here a part of global transcriptomic studies comparing the parasite transcriptome causing uncomplicated disease with severe Plasmodium vivax manifestations, namely hepatic dysfunction and cerebral malaria focusing on the vir genes, some of which have been postulated to be involved in cytoadherence

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